PCR Journal Club

The present study compares a novel sirolimus-coated balloon with a clinically proven paclitaxel-coated balloon for the treatment of de novo coronary lesions, demonstrating non-inferiority in terms of angiographic late lumen loss at 6 months.

This registry-based observational study demonstrated that, in patients with STEMI and LTB, TA failure was associated with reduced myocardial perfusion and increased all-cause and cardiovascular mortality.

Compared to fluoroscopy guidance, routine use of ultrasound for large-bore transfemoral access in complex PCI did not significantly reduce clinically relevant bleeding or vascular complications. However, it notably improved first-pass puncture success, with a very low crossover rate.

This study aims to evaluate changes in microcirculatory function post-TAVI, specifically assessing resting and hyperaemic absolute coronary flow and microvascular resistance before TAVI, immediately post, and at 6-month follow-up.

The present study explores the alternative of 1 suture-based + 1 plug closure device vs. the conventional one, finding a superiority of this approach in achieving the full closure, hemostasis with a reduced incidence of complications. 

The aim of this pre-specified analysis of the ILUMIEN IV trial was to assess the relationship between post-PCI OCT parameters of suboptimal stent implantation and clinical outcomes.

In this analysis, the 3-year outcomes of the TRILUMINATE study are presented, evaluating the long-term effectiveness of the TriClip T-TEER system on TR reduction, right ventricular remodeling, quality of life, and heart failure symptoms.

The current subanalysis of the BioVasc trial offers valuable insights into the long-term effects of ICR versus SCR strategies in STEMI patients with MVD. The findings support current guidelines on the necessity of revascularizing non-culprit lesions.

The review aims to address the unmet needs in heart failure (HF) management, particularly in patients where structural heart disease coexists with HF and limits the effectiveness of guideline-directed medical therapy (GDMT).

The rationale for this study was to provide direct evidence of colchicine's effects on plaque stabilization, particularly by assessing changes in plaque characteristics using optical coherence tomography (OCT).