
Ali Nazmi Calik
Latest contributions
Duration of DAPT in ACS: The DUAL-ACS Trial
31 Aug 2025
Ali Nazmi Calik interviews David Newby on the landmark DUAL-ACS trial results he presented at ESC Congress 2025 in Madrid.
The trial compared 3 months versus 12 months of dual antiplatelet therapy (DAPT) after myocardial infarction in an all-comer population. Findings suggest that shorter therapy may offer better...

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PCRonline @ ESC Congress 2025: the interventional cardiology perspective!
26 Jul 2025
Stay updated with the latest in interventional cardiology at #ESCCongress 2025!

Comparison of stent geometry achieved by different side-branch ballooning techniques for bifurcation provisional stenting: the CRABBIS Trial
31 Mar 2025
Which ballooning technique is best after main vessel stenting in bifurcation PCI? This two-part study compares two key approaches: PKP (POT, kissing balloon inflation, final POT) and PSP (POT, isolated side branch dilation, final POT) to determine the optimal strategy.

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Reviewer

Rotational atherectomy, lithotripsy, or laser for calcified coronary stenosis: the ROLLER COASTR-EPIC22 trial
24 Mar 2025
Due to a lack of randomised evidence, this randomised controlled trial (RCT) aimed to compare the safety and efficacy of IVL and ELCA with RA in treating heavily calcified coronary lesions before drug-eluting stent implantation.

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Reviewer

Usefulness of FFR-CT to exclude haemodynamically significant lesions in high-risk NSTE-ACS
07 Mar 2025
This single-arm, double-blinded, core-laboratory adjudicated, prospective trial, conducted across four European centers between August 2019 and April 2022, investigates whether CCTA and FFR-CT are able to exclude hemodynamically significant coronary stenoses in patients with high-risk NSTE-ACS.

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Reviewer

Angiography-derived fractional flow reserve versus intravascular ultrasound to guide percutaneous coronary intervention in patients with coronary artery disease: the FLAVOUR II trial
29 Mar 2025
Ali Nazmi Calik provides his take on the FLAVOUR II trial presented by Jian-An Wang at ACC.25 in Chicago.

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Routine cerebral embolic protection in transcatheter aortic valve implantation: the British Heart Foundation (BHF) PROTECT-TAVI trial
29 Mar 2025
Aaysha Cader and Ali Nazmi Calik provide their take on the BHF PROTECT-TAVI trial, presented by Rajesh Kharbanda at ACC.25 in Chicago.

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PCRonline @ ACC.25 Scientific Sessions
07 Feb 2025
Live updates on a selection of major Late Breaking Clinical Trials of interest in interventional cardiology presented at the American College of Cardiology 2025 Scientific Sessions #ACC25

Percutaneous vs. Surgical revascularization of non-ST-segment elevation myocardial infarction with multivessel disease: The SWEDEHEART registry
02 Jan 2025
This registry-based observational study compares surgical and percutaneous revascularization in patients with multivessel disease who underwent treatment for non-ST-segment elevation myocardial infarction (NSTEMI), utilizing data extracted from the SWEDEHEART registry.

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Reviewer

Complex non left main bifurcation PCI - LIVE case
19 Dec 2024 – From GulfPCR-GIM 2024
A 71-year-old male presented with angina (CCS 2), normal left ventricular function, and mitral stenosis. Coronary angiography revealed severe ostial stenosis of the circumflex artery and a significant LAD/diagonal bifurcation lesion (Medina 0.1.1).
The operators performed balloon valvuloplasty to treat the mitral stenosis, followed by LAD/diagonal PCI....

Best of science and education in cardiovascular interventional medicine in 2024
16 Dec 2024
Dear Colleagues, dear PCR Companions,
As we welcome a new year, it is the perfect time to reflect on what we achieved together over the past year—both as a celebration of our successes and as motivation to continue improving in the year ahead.
2024 was a record year...

Ultrasound-guided versus fluoroscopy-guided large-bore femoral access in PCI of complex coronary lesions: the international, multicentre, randomised ULTRACOLOR Trial
02 Dec 2024
Compared to fluoroscopy guidance, routine use of ultrasound for large-bore transfemoral access in complex PCI did not significantly reduce clinically relevant bleeding or vascular complications. However, it notably improved first-pass puncture success, with a very low crossover rate.

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Reviewer

Effective techniques for performing DCB angioplasty
16 Jan 2025
Drug-coated balloon (DCB) angioplasty has become a valuable alternative to drug-eluting stents in treating coronary artery disease. To achieve optimal outcomes, proper lesion preparation and techniques to minimise drug loss are crucial.
This article highlights key steps and best practices for performing DCB angioplasty, ensuring effective drug delivery and...

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Early intervention in patients with asymptomatic severe aortic stenosis and left ventricular myocardial fibrosis (EVOLVED)
30 Oct 2024
Ali Nazmi Calik provides his take on the EVOLVED trial presented by Marc Dweck at TCT 2024 in Washington.

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Immediate versus staged complete revascularisation in patients presenting with STEMI and multivessel disease
21 Oct 2024
The current subanalysis of the BioVasc trial offers valuable insights into the long-term effects of ICR versus SCR strategies in STEMI patients with MVD. The findings support current guidelines on the necessity of revascularizing non-culprit lesions.

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Reviewer

PCR @ TCT 2024 - Get the international perspective!
11 Oct 2024
Thanks to the contribution of a team of interventional cardiologists from around the globe, get the international perspective on Late-breaking Clinical Trials and Science released at TCT 2024 - check out the list below.

NOTION-3 - Percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation
01 Sep 2024
Make the most of the insights from Jacob Thomsen Loenborg’s interview with Chiara De Biase and Ali Nazmi Calik’s article to capture the key takeaways from this trial, simultaneously published in the NEJM, presented at the ESC Congress 2024 in London.

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PCRonline @ ESC Congress 2024: the interventional cardiology perspective!
26 Jul 2024
What was new and hot in interventional cardiology at #ESCCongress 2024!

Percutaneous coronary intervention for bifurcation coronary lesions using optimised angiographic guidance: the 18th Consensus Document from the European Bifurcation Club
24 Jun 2024
In coronary bifurcation lesions (CBL) PCI, intracoronary imaging (ICI) is preferred for its superior outcomes over angiography alone, but its adoption is limited by education and technology access barriers, resulting in most CBL PCIs still using angiographic guidance only.

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Reviewer

PCI of bifurcation lesions: management of complications - Part 1
16 May 2024 – From EuroPCR 2024
Explore strategies for managing complex PCI of bifurcation lesions through case discussions. From stent deformation and delicate diagonal wiring to wire fracture with snare failure, decoiled coronary guidewires, misplaced stents, spontaneous coronary artery dissection, and late tamponade after PCI, this session covers how to effectively respond...

Ostial LAD - Ostial circumflex
15 May 2024 – From EuroPCR 2024

Role of deferred stenting in culprit and non-culprit lesions for STEMI
14 May 2024 – From EuroPCR 2024
This session explores the role of deferred stenting in STEMI patients, covering when and how PCI can be deferred, the latest pharmacological options for deferred stenting, and the use of imaging and physiology to guide revascularization in a primary PCI setting. Through case presentations and discussions,...

Long-term beta-blocker treatment after acute myocardial infarction and preserved left ventricular ejection fraction: The REDUCE-AMI Trial
07 Apr 2024
REDUCE-AMI is a multicentre, registry-based, prospective open-label parallel-group randomised clinical trial evaluating the benefit of beta-blocker treatment in patients with acute MI and an ejection fraction >50% treated with a contemporary reperfusion strategy.
Nicola Ryan and Ali Nazmi Calik provide their take on the results which were presented...

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PCRonline @ ACC.24 Scientific Sessions
22 Mar 2024
Live updates on a selection of major Late Breaking Clinical Trials of interest in interventional cardiology presented at the American College of Cardiology 2024 Scientific Sessions #ACC24

Preventive PCI or medical therapy alone for atherosclerotic coronary vulnerable plaques (PREVENT)
08 Apr 2024
Ali Nazmi Calik provides his take on the results of the PREVENT trial presented at ACC.24 in Atlanta.

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Rethinking false positive exercise electrocardiographic stress tests by assessing coronary microvascular function
24 Jan 2024
This study aims to compare the results of EST in patients reporting angina with those having non-obstructive coronary artery disease (ANOCA), against the reference standard of microvascular function.

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Reviewer

Abstracts session 1
06 Dec 2023 – From GulfPCR-GIM 2023
Broaden your knowledge with this selection of abstracts submitted to GulfPCR-GIM 2023, covering topics such as aortic procedures, LV function recovery after CTO recanalization, and the state of PCI in the region of Kurdistan in Iraq.
Learning bifurcation PCI
06 Dec 2023 – From GulfPCR-GIM 2023
Through the case of a 72-year-old hypertensive patient presenting with chest pain that had been there for 15 days but had suddenly intensified, followed by that of a second patient suffering from side-branch stenosis, learn more about provisional stenting and the two-stent strategy, and explore the...

T-PASS: Less than 1-month DAPT followed by ticagrelor monotherapy after DES Implantation for ACS
26 Oct 2023
Ali Nazmi Calik interviews Myeong-Ki Hong about the results of the T-Pass randomised trial which he presented during the #TCT Congress 2023 in San Francisco.

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PCRonline @ TCT 2023 - Get the international perspective!
17 Oct 2023
Thanks to the contribution of our team of interventional cardiologists from around the globe, view the international perspective on Late-breaking Clinical Trials and Science to be released at TCT 2023 - check out the list here!
